Have connection but no response from server

This is what a section of the log looks like:

Resolving host name ip addr...
Connecting to (ip addr) -> IP: ip addr PORT: 21
Connected to (ip addr) -> Time = 0ms
Socket connected waiting for login sequence.
Connection timeout. No response from server.
Cannot login waiting to retry (30s)...

Am able to connect at a command prompt, login with the same name, password, create a directory, cwd to that work directory and I have uploaded a couple of files.

Yet I get nothing via SmartFTP. I have tried a number of settings changes. disabled my personal firewall and virus protection but no success.

Help!