JET Database Engine error '80004005'

when i try to access a site i get the following error

Microsoft JET Database Engine error '80004005'

'e:\public\wwwroot\customers\pegasus-glass\data\PEGIN1.mdb' is not a valid path. Make sure that the path name is spelled correctly and that you are connected to the server on which the file resides.

/LM/W3SVC/2/Root/includes/app_start.asp, line 32

the site have been working fine until i installed SmartFTP and used it to change html code on default.asp a little
im did a little search without any help
im pretty new to this stuff, so any tip or help would be appreciated

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