Connection failures

Can anyone tell me where I should look to resolve a connection problem reported as below?

[21:32:12] Resolving host name ""
[21:32:12] Connecting to Port: 21
[21:32:33] A connection attempt failed because the connected party did not properly respond after a period of time, or established connection failed because connected host has failed to respond.
[21:32:33] Client closed the connection.
[21:32:33] Connect failed. Waiting to retry (30s)...
[21:32:33] Active Help: