Need HELP! Badly

Hi Have several problems, perhaps someone out there could lend a hand... From frontpage I can upload onto Smart FTP but then where do I go from there? have tried logging into my domain but it comes up as Internat cannot show this page, I have tried uploading to my domain straight from frontpage but it juat sends an error maessage, "cannot set permissions for file".... I,m going out of my mind please help me.....Steve