A connection attempt failed

Hi I just recently installed SmartFTP 2.0 and when trying to make a connection I keep getting the following message.

A connection attempt failed because the connected party did not properly respond after a period of time, or established connection failed because connected host has failed to respond.

Does anyone have an idea of how to solve this?

I have made sure the firewall isn't blocking it and neither is Norton Antivirus 2005 Internet Worm Protection.